{"id":15,"date":"2026-06-13T09:32:52","date_gmt":"2026-06-13T07:32:52","guid":{"rendered":"https:\/\/publichealthtribune.com\/wuu\/2026\/06\/13\/%e4%b8%80%e5%8f%aa%e6%8a%97%e4%bd%93%e5%9c%a8%e5%87%8f%e8%82%a5%e8%bf%87%e7%a8%8b%e4%b8%ad%e4%bf%9d%e6%8a%a4%e8%82%8c%e8%82%89%e8%b4%a8%e9%87%8f\/"},"modified":"2026-06-13T09:34:10","modified_gmt":"2026-06-13T07:34:10","slug":"%e4%b8%80%e5%8f%aa%e6%8a%97%e4%bd%93%e5%9c%a8%e5%87%8f%e8%82%a5%e8%bf%87%e7%a8%8b%e4%b8%ad%e4%bf%9d%e6%8a%a4%e8%82%8c%e8%82%89%e8%b4%a8%e9%87%8f","status":"publish","type":"post","link":"https:\/\/publichealthtribune.com\/wuu\/2026\/06\/13\/%e4%b8%80%e5%8f%aa%e6%8a%97%e4%bd%93%e5%9c%a8%e5%87%8f%e8%82%a5%e8%bf%87%e7%a8%8b%e4%b8%ad%e4%bf%9d%e6%8a%a4%e8%82%8c%e8%82%89%e8%b4%a8%e9%87%8f\/","title":{"rendered":"\u4e00\u53ea\u6297\u4f53\u5728\u51cf\u80a5\u8fc7\u7a0b\u4e2d\u4fdd\u62a4\u808c\u8089\u8d28\u91cf"},"content":{"rendered":"

\"\u4e00\u53ea\u6297\u4f53\u5728\u51cf\u80a5\u8fc7\u7a0b\u4e2d\u4fdd\u62a4\u808c\u8089\u8d28\u91cf\"<\/p>\n

\u4e00\u53ea\u6297\u4f53\u5728\u51cf\u80a5\u8fc7\u7a0b\u4e2d\u4fdd\u62a4\u808c\u8089\u8d28\u91cf<\/h1>\n

\u901a\u8fc7\u50cftirz\u00e9patide\u8fd9\u6837\u7684\u6cbb\u7597\u5f15\u53d1\u7684\u51cf\u80a5\u901a\u5e38\u4f1a\u4f34\u968f\u808c\u8089\u8d28\u91cf\u7684\u51cf\u5c11\uff0c\u8fd9\u53ef\u80fd\u4f1a\u635f\u5bb3\u5065\u5eb7\u548c\u8eab\u4f53\u529f\u80fd\u3002\u6700\u8fd1\u7684\u4e00\u9879\u7814\u7a76\u8bc4\u4f30\u4e86\u6297\u4f53apitegromab\u5728\u9650\u5236\u8fd9\u79cd\u808c\u8089\u6d41\u5931\u65b9\u9762\u7684\u6709\u6548\u6027\u3002\u8fd9\u79cd\u6297\u4f53\u901a\u8fc7\u7279\u5f02\u6027\u963b\u65admyostatine\u7684\u6fc0\u6d3b\u6765\u53d1\u6325\u4f5c\u7528\uff0cmyostatine\u662f\u4e00\u79cd\u8c03\u8282\u808c\u8089\u5206\u89e3\u7684\u86cb\u767d\u8d28\u3002\u901a\u8fc7\u6291\u5236\u8fd9\u79cd\u86cb\u767d\u8d28\uff0capitegromab\u6709\u52a9\u4e8e\u589e\u52a0\u548c\u4fdd\u62a4\u808c\u8089\u8d28\u91cf\u3002<\/p>\n

\u8fd9\u9879\u7814\u7a76\u6d89\u53ca102\u540d\u8d85\u91cd\u6216\u80a5\u80d6\u7684\u6210\u5e74\u4eba\uff0c\u4ed6\u4eec\u88ab\u5206\u4e3a\u4e24\u7ec4\uff0c\u5206\u522b\u63a5\u53d7tirz\u00e9patide\u8054\u5408apitegromab\u6216tirz\u00e9patide\u8054\u5408\u5b89\u6170\u5242\u7684\u6cbb\u7597\u3002\u7ecf\u8fc724\u5468\u540e\uff0c\u63a5\u53d7apitegromab\u6cbb\u7597\u7684\u53c2\u4e0e\u8005\u5e73\u5747\u6bd4\u5b89\u6170\u5242\u7ec4\u5c11\u51cf\u5c111.9\u516c\u65a4\u808c\u8089\u8d28\u91cf\uff0c\u540c\u65f6\u603b\u4f53\u51cf\u91cd\u6548\u679c\u76f8\u4f3c\u3002\u8fd9\u76f8\u5f53\u4e8e\u76f8\u5bf9\u4e8e\u5b89\u6170\u5242\u7ec4\u4fdd\u62a4\u4e86\u8fd155%\u7684\u808c\u8089\u8d28\u91cf\u3002apitegromab\u548c\u6f5c\u5728myostatine\u7684\u6d53\u5ea6\u9010\u6e10\u589e\u52a0\uff0c\u5e76\u5728\u5927\u7ea616\u5468\u540e\u8fbe\u5230\u5e73\u53f0\u671f\uff0c\u8bc1\u5b9e\u4e86\u6cbb\u7597\u7684\u6709\u6548\u6027\u3002<\/p>\n

\u4e24\u7ec4\u4e4b\u95f4\u7684\u4e0d\u826f\u53cd\u5e94\u662f\u53ef\u6bd4\u7684\uff0c\u4e3b\u8981\u662f\u8f7b\u5ea6\u548c\u6682\u65f6\u6027\u7684\u4e8b\u4ef6\u3002\u6ca1\u6709\u62a5\u544a\u4e0eapitegromab\u76f8\u5173\u7684\u4e25\u91cd\u4e0d\u826f\u53cd\u5e94\u3002\u7ed3\u679c\u8868\u660e\uff0capitegromab\u901a\u8fc7\u9009\u62e9\u6027\u9776\u5411myostatine\uff0c\u53ef\u4ee5\u5728\u4e0d\u5f71\u54cd\u8102\u80aa\u51cf\u5c11\u7684\u60c5\u51b5\u4e0b\u4fdd\u62a4\u808c\u8089\u8d28\u91cf\uff0c\u4ece\u800c\u4e3a\u80a5\u80d6\u6cbb\u7597\u7684\u4eba\u63d0\u4f9b\u4e00\u79cd\u6709\u524d\u666f\u7684\u65b9\u6cd5\u3002<\/p>\n

Myostatine\u662f\u4e00\u79cd\u5929\u7136\u86cb\u767d\u8d28\uff0c\u9650\u5236\u4e86\u808c\u8089\u7684\u751f\u957f\u3002apitegromab\u5bf9\u5176\u9009\u62e9\u6027\u6291\u5236\u5728\u52a8\u7269\u6a21\u578b\u548c\u810a\u9ad3\u6027\u808c\u840e\u7f29\u75c7\u60a3\u8005\u4e2d\u5df2\u5c55\u73b0\u51fa\u76ca\u5904\uff0c\u8fdb\u4e00\u6b65\u589e\u5f3a\u4e86\u5176\u6cbb\u7597\u6f5c\u529b\u3002\u53c2\u4e0e\u8005\u7684\u8102\u80aa\u51cf\u5c11\u5728\u603b\u51cf\u91cd\u4e2d\u6240\u5360\u6bd4\u4f8b\u66f4\u5927\uff0c\u8fd9\u5bf9\u4ee3\u8c22\u5065\u5eb7\u6709\u76ca\u3002<\/p>\n

\u8fd9\u9879\u7814\u7a76\u8bc1\u5b9e\uff0capitegromab\u901a\u8fc7\u4f5c\u7528\u4e8e\u4e00\u4e2a\u660e\u786e\u7684\u751f\u7269\u673a\u5236\uff0c\u53ef\u4ee5\u51cf\u8f7b\u51cf\u80a5\u6cbb\u7597\u76f8\u5173\u7684\u808c\u8089\u6d41\u5931\uff0c\u540c\u65f6\u4fdd\u6301\u826f\u597d\u7684\u8010\u53d7\u6027\u3002\u8fd9\u4e9b\u7ed3\u679c\u4e3a\u6539\u5584\u836f\u7269\u51cf\u80a5\u671f\u95f4\u7684\u8eab\u4f53\u6210\u5206\u5f00\u8f9f\u4e86\u65b0\u7684\u7b56\u7565\u3002<\/p>\n

\n

\u00c0 propos de nos sources<\/h2>\n

Publication originale<\/h3>\n

DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1038\/s41591-026-04440-4<\/a><\/p>\n

Titre\u00a0:<\/strong> Apitegromab for lean mass preservation during tirzepatide-induced weight loss: a randomized, double-blind, placebo-controlled phase 2 trial<\/p>\n

Revue : <\/strong> Nature Medicine<\/p>\n

\u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n

Auteurs : <\/strong> Richard E. Pratley; Douglas Scott Denham; Rupal Trivedi; Elaine Watkins; Lisa Connery; Jennifer Barnes; Dongzi Yu; Janet Hong; Christopher Simard; Kimberly Umans; Lan Liu; Giridhar S. Tirucherai; Jing L. Marantz<\/p>\n","protected":false},"excerpt":{"rendered":"

\u4e00\u53ea\u6297\u4f53\u5728\u51cf\u80a5\u8fc7\u7a0b\u4e2d\u4fdd\u62a4\u808c\u8089\u8d28\u91cf \u901a\u8fc7\u50cftirz\u00e9patide\u8fd9\u6837\u7684\u6cbb\u7597\u5f15\u53d1\u7684\u51cf\u80a5\u901a\u5e38\u4f1a\u4f34\u968f\u808c\u8089\u8d28\u91cf\u7684\u51cf\u5c11\uff0c\u8fd9… \u7ee7\u7eed\u9605\u8bfb\u4e00\u53ea\u6297\u4f53\u5728\u51cf\u80a5\u8fc7\u7a0b\u4e2d\u4fdd\u62a4\u808c\u8089\u8d28\u91cf<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-15","post","type-post","status-publish","format-standard","hentry","category-2","entry"],"_links":{"self":[{"href":"https:\/\/publichealthtribune.com\/wuu\/wp-json\/wp\/v2\/posts\/15","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/publichealthtribune.com\/wuu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/publichealthtribune.com\/wuu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/publichealthtribune.com\/wuu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/publichealthtribune.com\/wuu\/wp-json\/wp\/v2\/comments?post=15"}],"version-history":[{"count":1,"href":"https:\/\/publichealthtribune.com\/wuu\/wp-json\/wp\/v2\/posts\/15\/revisions"}],"predecessor-version":[{"id":16,"href":"https:\/\/publichealthtribune.com\/wuu\/wp-json\/wp\/v2\/posts\/15\/revisions\/16"}],"wp:attachment":[{"href":"https:\/\/publichealthtribune.com\/wuu\/wp-json\/wp\/v2\/media?parent=15"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/publichealthtribune.com\/wuu\/wp-json\/wp\/v2\/categories?post=15"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/publichealthtribune.com\/wuu\/wp-json\/wp\/v2\/tags?post=15"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}