Long COVID Durably Reduces the Quality of Life of Japanese Adults
A recent study reveals that long COVID deeply affects the health-related quality of life of adults in Japan. Individuals affected by this condition have a significantly lower quality of life score than those who do not suffer from it, and this deterioration persists for a period of one year after the initial infection. Among the participants, those with pre-existing lung diseases experience an even more pronounced decline in their well-being.
Researchers have identified three distinct groups of long COVID patients, classified according to the severity and nature of their symptoms. The first group, the most numerous, exhibits mild and infrequent symptoms, yet their quality of life remains lower than that of unaffected individuals. The second group is characterized by persistent headaches, sore throats, and nasal congestion. The third, though smaller in number, suffers from more severe and varied symptoms, such as extreme fatigue, coughing, pain, and a loss of energy. Their quality of life then drops drastically, reaching particularly low levels.
Women, young adults, and individuals with a low body mass index or prior psychological disorders are particularly vulnerable. Their quality of life deteriorates further, especially in social, emotional, and physical domains. Even a slight increase in the number of long COVID symptoms leads to a notable decline in overall well-being.
The results also show that fatigue, headaches, pain, and respiratory problems are among the most frequent symptoms in the most affected patients. If these issues persist, they severely limit daily activities, social interactions, and vitality. Individuals with a history of lung diseases see their quality of life decline more sharply, even after recovering from the acute infection.
This study highlights the importance of prolonged medical follow-up and tailored care for long COVID patients, particularly for those with multiple symptoms or pre-existing health conditions. Interventions must address both physical and mental aspects to limit the lasting impact of this condition on individuals’ lives.
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Original Publication
DOI: https://doi.org/10.1007/s11136-026-04284-y
Title: Impact of long COVID on health-related quality-of-life among Japanese adults: findings of CARE Japan study
Journal: Quality of Life Research
Publisher: Springer Science and Business Media LLC
Authors: Sabera Sultana; Yusuke Asai; Haruhiko Ishioka; Shinichiro Ikeda; Anna Ohtera; Nobuaki Matsunaga; Norio Ohmagari; Shinya Tsuzuki